The anti-arthritic effects of Granadol® are linked to multiple mechanisms
1.Granadol® contains a broad variety of polyphenolics compounds, that inhibit reactions producing reactive oxygen species (ROS) à Inhibition of NF-κB, Inflammasome pathway & auto-amplification.
2.Granadol® contains polyunsaturated fatty acids (PUFAs), which act as agonists for PPARs receptors à Early inhibition of NF-κB, JNK, and p38-MAPK.
Today, there is no available treatment that manage the abnormal bones resorption. Granadol® is a first-in-class active ingredient.
Work in progress
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